homeobox proteins การใช้
- The NKX3-1 homeobox protein is encoded by the " NKX3-1 " gene.
- The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins.
- Homeobox proteins have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species.
- Mice _ and people, with their five-digit paws _ have a stretch of 15 alanines in the homeobox protein.
- The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus.
- Homeobox protein Nkx-2.2 contains a homeobox domain and may be involved in the morphogenesis of the central nervous system.
- This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.
- A third protein identified by yeast two-hybrid screening as a physical interactant of FAM46B is PEPP2, a paired-like homeobox protein.
- The homeobox protein Hox-A1 may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.
- Interaction between homeobox protein NANOG and Tet methylcytosine dioxygenase 1 ( TET1 ) has been shown to be important in establishing pluripotency during the generation of induced pluripotent stem cells.
- Genetics can do a lot of shaping via overlayed secretion of transcriptions factors, especially homeobox proteins; they are crucial for evolution of anatomy features .-talk ) 05 : 38, 24 November 2013 ( UTC)
- The "'ALX3 gene "', also known as aristaless-like homeobox 3, is a protein coding gene that provides instructions to build a protein which is a member of the homeobox protein family.
- MTA1 suppresses transcription of breast cancer type 1 susceptibility gene, PTEN, p21 WAF, guanine nucleotide-binding protein G ( i ) subunit alpha-2, nuclear receptor subfamily 4 group A member 1, and homeobox protein SIX3, and represses BCL11B as well as E-cadherin expression.
- When an enhancer box of a promoter that has been bound by the Ngn-2 / enhancer protein complex is also bound by a dimer of the adaptor nuclear LIM interactor ( NLI ) bound to two LIM homeobox protein 3 ( Lhx3 ), genes related to V2 interneuron identity are expressed.
- This hypothesis was substantiated when pre-mir-155 transduced HSPCs generated 5-fold fewer myeloid and 3-fold fewer erythroid colonies . demonstrated that the homeobox protein, HOXA9, regulated " MIR155HG " expression in myeloid cells and that this miRNA played a functional role in hematopoiesis.
- People with two copies of the risk allele for the rs9939609 single nucleotide polymorphism ( SNP ) showed differing neural responses to food images via fMRI . However, rs9939609's association with " FTO " is controversial, and may actually affect another gene, called iroquious homeobox protein 3 ( " IRX3 " ).
- SNAI1 / Snail 1, SNAI2 / Snail 2 ( also known as Slug ), ZEB1, ZEB2, E47 and KLF8 ( Kruppel-like factor 8 ) can bind to E-cadherin promoter and repress its transcription, whereas factors such as Twist, Goosecoid, E2.2 ( also known as TCF4 ), homeobox protein SIX1 and FOXC2 ( fork-head box protein C2 ) repress E-cadherin indirectly.